Professor Emeritus
Email: gshaw@ufl.edu
Website: http://www.encorbio.com/
Education:
| 1975 | BSc (Zoology) | Department of Zoology, University College London, England |
| 1980 | PhD (Zoology) | Department of Biophysics, King’s College London, England |
| 1980-1981 | Postdoctoral Fellowship | Max Planck Institute for Biophysical Chemistry, Gottingen, Germany |
Professional Experience:
| 1982-1986 | Staff Member, Max Planck Institute for Biophysical Chemistry, Gottingen, Germany |
| 1986-1991 | Assistant Professor, Department of Neuroscience, University of Florida, Gainesville, FL |
| 1991-1996 | Associate Professor, Department of Neuroscience, University of Florida, Gainesville, FL |
| 1996-2013 | Professor, Department of Neuroscience, University of Florida, Gainesville, FL |
| March 2013 | Retired as Professor Emeritus |
| December 2002-present | Founder and Ownder of EnCor Biotechnology, Inc., Gainesville, FL |
Key Words: Cytoskeleton,Neurodegenerative Disease,Neurofilaments,Biomarkers,Antibodies
Research Focus:
I am primarily interested in cellular changes as a result of neurodegenerative disease and damage states. The major tools I use are antibody reagents and assays made using these reagents, and one recent focus has been on the validation of phosphorylated axonal forms of NF-H (pNF-H) as a CSF and blood biomarker of axonal loss in a variety of damage and disease states. A second project looks at the potential use of ubiquitin C-terminal hydrolase 1 (UCHL1) as a potential blood and CSF biomarker of cortical injury and degeneration. We have also developed a novel and high quality assay for alpha-synuclein, a Parkinson’s disease related protein which we have shown can be detected in an altered form in the blood of Parkinson’s disease patients. Studies of other potential biomarkers are in progress. I can also initiate, fund and perform projects that particularly interest me in EnCor Biotechnology Inc., my independent privately funded corporate laboratory.
