Large-scale protein analysis of Alzheimer’s disease (AD) in the brain and cerebrospinal fluid reveals new associations with early changes in energy metabolism, according to research from UF neuroscientists. Findings revealed these early changes in energy metabolism to be associated with microglia and astrocyte activation. Because the pathophysiology of Alzheimer’s disease…
In a new perspective piece in the journal Trends in Cognitive Sciences, UF neuroscientist Andrew Mauerer, Ph.D., and University of psychologist Lynn Nadel, Ph.D., highlight the role of the hippocampus in spatial cognition and episodic memory. Andrew Maurer, Ph.D. (center). [This image was taken prior to national guidelines of…
UF Neuroscientists look deeper into dystrophic microglia in late-onset Alzheimer’s disease (AD). Studies conducted were done so by neuropathological analysis of post-mortem human brains with special attention paid to microglia, as these cells are important in cellular processes that lead to AD-type neurodegeneration. After finding an in situ correlation between…
Neuroscientists from University of Florida investigate plasma proteins’ influence on peripheral and central inflammation in depression. Peripheral blood C-reactive protein (CRP) is a biomarker used clinically to measure systemic inflammation. Patients with major depressive disorder (MDD) show increased amounts of CRP. Increased peripheral blood CRP in MDD has been associated…
University of Florida neuroscientists make breakthroughs in research regarding Parkinson’s disease (PD) in rodent model. The findings indicate both dopamine neuron loss protection and improved motor deficits due to alterations with gut microbiota and antibiotics. With PD affecting approximately 10 million worldwide with degeneration of motor and non-motor…
Read the Latest from the Khoshbouei Group New study from the University of Florida Department of Neuroscience finds anti-inflammatory agents do not yield beneficial effects in treating addiction disorders. Methamphetamine (METH), a psychostimulant subject to abuse worldwide, is widely recognized for its effects on dopamine neurotransmission and the central nervous…
Kalene Jasso was awarded a new individual predoctoral fellowship from NIH entitled “The Role of MCHR1 Signaling in Olfactory Function”. The goal of this project is to increase our understanding of mechanisms that modulate the sense of smell. The project will investigate the role of the melanin-concentrating hormone receptor (MCHR1) in…
Dr. Ashok Kumar, a Research Associate Professor in the Department of Neuroscience was recently awarded a new R21 from NIA entitled Age-associate impaired executive function: Rescue by NMDA receptor upregulation.
Learn about our Ph.D. program on Oct. 7 and 21 at 6:30 p.m. EST via zoom
UF neuroscience postdoc Brittney Yegla, Ph.D., is among featured speakers from across the world who will present at the 2nd Workshop on Research Definitions for Reserve and Resilience in Cognitive Aging and Dementia, to be held virtually Sept. 14 and 15. Yegla will present at 10:15 a.m. on Sept. 15…
