Neuroscience-MBI Microscope Co-op (NMC): A Shared Microscopy Resource for UF Neuroscientists

The NMC at UF operates a collection of PI-owned imaging systems and is managed by the Department of Neuroscience Research Committee.

About the NMC at UF

At the Department of Neuroscience and McKnight Brain Institute (MBI), we understand the financial constraints that many labs face when it comes to purchasing cutting-edge microscopes. To overcome this challenge, we have established a shared microscope resource that enables MBI-affiliated faculty members to pool their resources and share their existing microscopes with the entire research community. By joining forces, we can eliminate the need for multiple labs to invest in identical microscopes, allowing us to allocate resources more efficiently.

Click below to understand the check-out process and review the terms of agreement for all prospective NMC participants.

Instrument and Project Consultations

Portrait of Doctor Jason Coleman

In our ongoing commitment to enhanced productivity and data reproducibility, we’re pleased to welcome Dr. Jason Coleman to our team. With over 20 years of experience in quantitative imaging research within the neuroscience field, Dr. Coleman brings invaluable expertise to several critical areas.

As part of his role, Dr. Coleman will provide comprehensive training and consultation on co-op microscopy systems, ensuring optimal utilization of our imaging resources. Additionally, he will offer unbiased imaging assistance and guidance on rigorous data analysis methods, fostering a culture of accuracy and reliability in our research endeavors.

Dr. Coleman earned his PhD in neuroscience from the University of Florida and subsequently served as an HHMI postdoctoral fellow and research scientist at the Massachusetts Institute of Technology under the mentorship of Dr. Mark Bear. His extensive background in neuroscience encompasses expertise in neural tracing/labeling, somatic gene transfer techniques, and 3D/4D laser-scanning confocal and two-photon microscopy. He specializes in applying these methods to study detailed neural circuit architecture and function during neural plasticity, brain injury, and disease.

With his unique skill set and unwavering enthusiasm, Dr. Coleman is poised to make significant contributions to our current and future projects. We’re thrilled to have him on board and eager to leverage his expertise to advance our collective goals in the wider UF neuroscience research community.

Resources

Below you’ll find a list of available resources. If you would like to use any of them in a current of future research project, please click the title below to see how to access training and their schedules.

high-throughput fluorescence

Keyence BZ-X700

An all-in-one life science microscope that can easily observe, capture, and analyze images in fluorescence, brightfield, and phase contrast without the need for a darkroom.

photo of microscope

Zeiss Lightsheet Z1

Equipped with with Life Canvas SmartBatch+ Tissue Clearing and Immunolabeling System and 4 laser lines, a mesocale imaging system and 2.5x, 5x, and 12x objectives compatible with organic solvent clearing methodologies.

photo of microscope

inverted 2-photon/Confocal/STORM

Nikon A1R MP

Laser-scanning confocal (LSCM), multiphoton (MP), and N-STORM (super-resolution) inverted microscope for fluorescent samples. Available Tokai-Hit stage top incubator with active CO2 and temperature regulation, and passive humidity, for imaging live tissue/cells. 

photo of microscope

upright 2-photon/in vivo

Scientifica HyperScope

This system is optimized for imaging approaches that allow collection of signal emitting from deep tissues from live subjects. The microscope is equipped with the InSight X3 Dual variable+fixed IR lasers, SomnoSuite low-flow anesthesia station, and custom stages for intravital imaging.

photo of microscope