Skip to main content Skip to main menu
UF Health University of Florida
Department of Neuroscience College of Medicine
Give
Maurice S Swanson

Maurice S Swanson,

Professor and Associate Program Director

Department: Molecular Genetics & Microbiology
Business Phone: (352) 273-8076
Business Email: mswanson@ufl.edu

On This Page

About Maurice S Swanson

Fun Fact: I love to snow ski and play ice hockey.

Our research group focuses on how RNA processing is controlled during mammalian development and how this regulation is disrupted in neurological and neuromuscular diseases. More than half of the human genome is comprised of repetitive elements, including interspersed and tandem repeats, and more than 60 hereditary diseases are caused by the expansion of short tandem repeats (STRs). We investigate the functions of these genomic elements using a wide array of biochemical (e.g., transcriptomics, proteomics) and genetic (e.g., gene knockout and knockin models) strategies. Additionally, we study how RNA binding proteins (RBPs) interact with various RNA structures using global analysis of RBP binding sites, the functions of nuclear RNA foci (biomolecular condensates) generated by pathogenic STR expansions, and how RNA-based mechanisms promote mammalian tissue regeneration. Finally, we are developing novel cell and mouse models to test therapeutic strategies designed to block the toxicity of repetitive element mutations.

Related Links:
Center for NeuroGenetics
MGM Lab and Research Information

Teaching Profile

Courses Taught

  1. GMS7980 – Research for Doctoral Dissertation

    College of Medicine

  2. GMS7979 – Advanced Research

    College of Medicine

  3. GMS6290 – Genetics/Genomics Program Graduate Seminar

    College of Medicine

  4. BCH6415 – Advanced Molecular and Cell Biology

    College of Medicine

  5. GMS6001 – Fundamentals of Biomedical Sciences I

    College of Medicine

  6. BCH7410 – Advanced Gene Regulation

    College of Medicine

  7. GMS5905 – Special Topics in Biomedical Sciences

    College of Medicine

Research Profile

Areas of Interest

  • Aging
  • Developmental regulation of RNA processing
  • Genetics of Neurological diseases
  • Mammalian genome repetitive elements
  • Mechanisms of Regeneration
  • Myotonic Dystrophy
  • Neurological disorders
  • RNA binding proteins

Publications

Academic Articles

Grants

Education

  1. PhD

    University of California Berkeley

  2. MA

    University of California Santa Barbara

Contact Details

Phones:
Business:
(352) 273-8076
Emails:
Business:
mswanson@ufl.edu
Addresses:
Business Mailing:
2033 MOWRY RD
 GAINESVILLE FL 32610
Business Street:
Cancer Genetics Research Complex
College of Medicine, 2033 Mowry Rd
DEPT. OF MOLECULAR GENETICS AND MICROBIOLOGY
 GAINESVILLE FL 326103610