Brian L Hoh

Brian L Hoh, MD, MBA, FACS, FAHA, FAANS

Chair; Lillian S. Wells Department Of Neurosurgery James And Brigitte Marino Family Professor

Department: MD-NEUROLOGICAL SURGERY
Business Phone: (352) 273-9000

About Brian L Hoh

Brian Hoh, MD, MBA, FACS, FAHA, FAANS, is an internationally known expert in the treatment of brain aneurysms, brain arteriovenous malformations, and ischemic and hemorrhagic stroke. He is the chair of the Lillian S. Wells Department of Neurosurgery at the University of Florida College of Medicine.

Dr. Hoh graduated from Stanford University with a Bachelor of Arts and Science degree in biology and political science. He attended medical school at Columbia University in New York, where he graduated with Alpha Omega Alpha honors. Dr. Hoh completed his internship in surgery, residency in neurological surgery and fellowship in interventional neuroradiology at Harvard University at Massachusetts General Hospital. He graduated with an MBA from the University of Florida Hough Graduate School of Business with Beta Gamma Sigma honors.

Dr. Hoh is board-certified by the American Board of Neurological Surgery (ABNS) with additional certification of Recognition of Focused Practice by the ABNS for CNS Endovascular Surgery.

Dr. Hoh is a national leader in neurosurgery. He is past-President of the Congress of Neurological Surgeons, past-chair of the Joint American Association of Neurological Surgeons/Congress of Neurosurgical Surgeons Cerebrovascular Section, a member of the American Academy of Neurological Surgery, the Society of Neurological Surgeons, the American Association of Neurological Surgeons, the Florida Neurosurgical Society and a senior member of the Society for Neurointerventional Surgery.

Dr. Hoh is a past co-chair and member of the editorial board of the Journal of Neurosurgery and a past member of the editorial board of the Journal World Neurosurgery.

Dr. Hoh is an NIH-U01-funded principal investigator of the CAPTIVA (Comparison of Anticoagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis) Trial, an NIH StrokeNet multicenter prospective double-blinded randomized trial for stroke prevention in patients with symptomatic intracranial atherosclerotic stenosis.

Dr. Hoh is an NIH-R01-funded principal investigator of basic science research investigating the biologic mechanisms of cerebral aneurysm formation and rupture, as well as innovative tissue engineering technology to improve the treatment of cerebral aneurysms. He is also an investigator on national and international clinical trials focused on stroke, cerebral aneurysms, carotid stenting and endarterectomy, and vasospasm.

Dr. Hoh is a leader in neurosurgical education. He is the past director of the UF residency program and the UF endovascular surgical neuroradiology fellowship program, both ACGME-accredited training programs. In these roles, he was responsible for the training of 21 neurosurgery residents and endovascular surgical neuroradiology fellows.

Accomplishments

Exemplary Teacher Award
2014 · University of Florida
Byron Cone Pevehouse Award for Socio-Economic Research
2012 · American Association of Neurological Surgeons
Exemplary Teacher Award
2010 · University of Florida
Excellence in Teaching Incentive Award
2009 · University of Florida
Robert D. Florin Award for Socio-Economic Research
2009 · American Association of Neurological Surgeons
Exemplary Teacher Award
2008 · University of Florida
Excellence in Teaching Incentive Award
2007 · University of Florida

Teaching Profile

Courses Taught
2018
MDC7600 Surgery Clerkship
2018
MDT7090 Elective Topics
2018
MDT7650 Elect Top/Neurol Surg
2018
GMS7979 Advanced Research
2017
BMS4905 Medical Sciences Senior Research
2009
MEL7931 Elect Top/Neurol Surg

Board Certifications

  • Neurological Surgery
    American Board of Neurological Surgery

Clinical Profile

Specialties
  • Neurosurgery
Areas of Interest
  • Angioplasty and stent placement – carotid artery
  • Brain tumor – primary – adults
  • Carotid artery disease
  • Carotid artery surgery – open
  • Cerebral aneurysm
  • Cerebral arteriovenous malformation
  • Chiari malformations
  • Glioblastoma multiforme
  • Meningioma
  • Metastatic brain tumor
  • Moyamoya disease
  • Normal pressure hydrocephalus

Research Profile

Research Activities include: Craniotomy, Aneurysm clipping, Carotid endarterectomy, Resection of intracranial arteriovenous malformations, Resection of spinal arteriovenous malformations, EC-IC bypass for complex aneurysm, ischemic stroke, and Moyamoya disease, and Brain tumors

Areas of Interest
  • Adult Brain Tumors
  • Aneurysm Clipping
  • Carotid Endarterectomy
  • EC-IC bypass for complex aneurysm, ischemic stroke and Moyamoya disease
  • Resection of intracranial arteriovenous malformations
  • Resection of spinal arteriovenous malformations
  • craniotomy
Open Researcher and Contributor ID (ORCID)

0000-0002-4997-4469

Publications

2022
Combination release of chemokines from coated coils to target aneurysm healing.
Journal of neurointerventional surgery. [DOI] 10.1136/neurintsurg-2022-018710. [PMID] 35609975.
2022
Intracranial atherosclerotic stenosis: risk factors, diagnosis, and treatment.
The Lancet. Neurology. 21(4):355-368 [DOI] 10.1016/S1474-4422(21)00376-8. [PMID] 35143758.
2022
Sensorineural hearing loss due to delayed cerebral ischemia in bilateral auditory cortices following aneurysmal subarachnoid hemorrhage: illustrative case.
Journal of neurosurgery. Case lessons. 3(19) [DOI] 10.3171/case21700. [PMID] 35712049.
2022
Severe headache trajectory following aneurysmal subarachnoid hemorrhage: the association with lower sodium levels.
Brain injury. 36(4):579-585 [DOI] 10.1080/02699052.2022.2055146. [PMID] 35353644.
2022
Ticagrelor resistance: a case series and algorithm for management of non-responders.
Journal of neurointerventional surgery. 14(2):179-183 [DOI] 10.1136/neurintsurg-2021-017638. [PMID] 34215660.
2022
Timing surgery and hemorrhagic complications in endocarditis with concomitant cerebral complications.
Clinical neurology and neurosurgery. 214 [DOI] 10.1016/j.clineuro.2022.107171. [PMID] 35180644.
2022
Understanding the genetics of intracranial aneurysms: A primer.
Clinical neurology and neurosurgery. 212 [DOI] 10.1016/j.clineuro.2021.107060. [PMID] 34863053.
2021
A Modification to a Murine Model for Intracranial Aneurysm Formation and Rupture.
Cureus. 13(7) [DOI] 10.7759/cureus.16250. [PMID] 34373811.
2021
Adropin decreases endothelial monolayer permeability after cell-free hemoglobin exposure and reduces MCP-1-induced macrophage transmigration
Biochemical and Biophysical Research Communications. 582:105-110 [DOI] 10.1016/j.bbrc.2021.10.032. [PMID] 34710824.
2021
Aneurysmal Subarachnoid Hemorrhage in Patients with Coronavirus Disease 2019 (COVID-19): A Case Series.
World neurosurgery. 153:e259-e264 [DOI] 10.1016/j.wneu.2021.06.092. [PMID] 34242830.
2021
Association Between Hospital Volumes and Clinical Outcomes for Patients With Nontraumatic Subarachnoid Hemorrhage.
Journal of the American Heart Association. 10(15) [DOI] 10.1161/JAHA.120.018373. [PMID] 34325522.
2021
Commentary: Developing a Professionalism and Harassment Policy for Organized Neurosurgery.
Neurosurgery. 89(1) [DOI] 10.1093/neuros/nyab113. [PMID] 33989416.
2021
Interleukin-6: Important Mediator of Vasospasm Following Subarachnoid Hemorrhage.
Current neurovascular research. 18(3):364-369 [DOI] 10.2174/1567202618666211104122408. [PMID] 34736380.
2021
Moyamoya Disease in a Young Female With Neurofibromatosis Type 1.
Cureus. 13(10) [DOI] 10.7759/cureus.19121. [PMID] 34858759.
2021
NLRP3 inhibition attenuates early brain injury and delayed cerebral vasospasm after subarachnoid hemorrhage.
Journal of neuroinflammation. 18(1) [DOI] 10.1186/s12974-021-02207-x. [PMID] 34284798.
2021
Pathophysiology of Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: A Review.
Journal of the American Heart Association. 10(15) [DOI] 10.1161/JAHA.121.021845. [PMID] 34325514.
2021
Trends in Hospital-to-Hospital Transfers for Aneurysmal Subarachnoid Hemorrhage: A Single-Institution Experience from 2006 to 2017.
World neurosurgery. 148:e17-e26 [DOI] 10.1016/j.wneu.2020.11.111. [PMID] 33359879.
2021
Trends of Acute Ischemic Stroke Reperfusion Therapies from 2012 to 2016 in the United States.
World neurosurgery. 150:e621-e630 [DOI] 10.1016/j.wneu.2021.03.073. [PMID] 33757890.
2020
Carotid Revascularization and Its Effect on Cognitive Function: A Prospective Nonrandomized Multicenter Clinical Study.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 29(5) [DOI] 10.1016/j.jstrokecerebrovasdis.2020.104702. [PMID] 32107155.
2020
Cigarette smoking and risk of intracranial aneurysms in middle-aged women.
Journal of neurology, neurosurgery, and psychiatry. 91(9):985-990 [DOI] 10.1136/jnnp-2020-323753. [PMID] 32723730.
2020
Comparing Standard Performance and Outcome Measures in Hospitalized Pituitary Tumor Patients with Secretory versus Nonsecretory Tumors.
World neurosurgery. 135:e510-e519 [DOI] 10.1016/j.wneu.2019.12.059. [PMID] 31863896.
2020
Interleukin-6 Promotes Murine Estrogen Deficiency-Associated Cerebral Aneurysm Rupture.
Neurosurgery. 86(4):583-592 [DOI] 10.1093/neuros/nyz220. [PMID] 31264696.
2020
Laboratory assessments of therapeutic platelet inhibition in endovascular neurosurgery: complication prediction using the VerifyNow P2Y12 assay and thromboelastography with platelet mapping
Journal of Neurosurgery. 134(3):1-9 [DOI] 10.3171/2019.12.JNS192396. [PMID] 32084635.
2020
Letter to the Editor. Education and evidence-based medicine in neurosurgery.
Journal of neurosurgery. Spine. 1-2 [DOI] 10.3171/2019.12.SPINE191505. [PMID] 32114529.
2020
Off-Label Utilization of Syphontrak Catheter for Mechanical Thrombectomy in Acute Stroke.
World neurosurgery. 143:e106-e111 [DOI] 10.1016/j.wneu.2020.06.235. [PMID] 32653512.
2020
The Evolution of Flow-Diverting Stents for Cerebral Aneurysms; Historical Review, Modern Application, Complications, and Future Direction
Journal of Korean Neurosurgical Society. 63(2):137-152 [DOI] 10.3340/jkns.2020.0034. [PMID] 32120455.
2019
A phase II randomized controlled trial of tiopronin for aneurysmal subarachnoid hemorrhage.
Journal of neurosurgery. 1-9 [DOI] 10.3171/2019.4.JNS19478. [PMID] 31299655.
2019
Anterior spinal artery aneurysm presenting with spinal subarachnoid hemorrhage in a case of polyarteritis nodosa.
Clinical imaging. 56:108-113 [DOI] 10.1016/j.clinimag.2019.04.008. [PMID] 31029009.
2019
Common Data Elements for Unruptured Intracranial Aneurysms and Aneurysmal Subarachnoid Hemorrhage: Recommendations from the Working Group on Hospital Course and Acute Therapies-Proposal of a Multidisciplinary Research Group.
Neurocritical care. 30(Suppl 1):36-45 [DOI] 10.1007/s12028-019-00726-3. [PMID] 31119687.
2019
Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.
Stroke. 50(12):e344-e418 [DOI] 10.1161/STR.0000000000000211. [PMID] 31662037.
2019
Localized Intra-Arterial Gene Delivery Using AAV.
Methods in molecular biology (Clifton, N.J.). 1937:259-265 [DOI] 10.1007/978-1-4939-9065-8_16. [PMID] 30706402.
2019
Nimodipine pharmacokinetics after intraventricular injection of sustained-release nimodipine for subarachnoid hemorrhage.
Journal of neurosurgery. 1-7 [DOI] 10.3171/2019.9.JNS191366. [PMID] 31812149.
2019
Race and socioeconomic disparity in treatment and outcome of traumatic cervical spinal cord injury with fracture: Nationwide Inpatient Sample database, 1998-2009.
Spinal cord. 57(10):858-865 [DOI] 10.1038/s41393-019-0280-6. [PMID] 30992516.
2019
Reimbursement patterns for neurosurgery: Analysis of the NERVES survey results from 2011-2016.
Clinical neurology and neurosurgery. 184 [DOI] 10.1016/j.clineuro.2019.105406. [PMID] 31302381.
2019
Single-Center Case Series of Temporary Stent Assistance for Coiling of Acutely Ruptured Aneurysms.
World neurosurgery. 123:e766-e772 [DOI] 10.1016/j.wneu.2018.12.029. [PMID] 30579035.
2019
Solitaire Stent Retriever Mechanical Thrombectomy in a 6-Month-Old Patient with Acute Occlusion of the Internal Carotid Artery Terminus: Case Report.
World neurosurgery. 126:631-637 [DOI] 10.1016/j.wneu.2019.03.038. [PMID] 30877002.
2018
2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.
Stroke. 49(3):e46-e110 [DOI] 10.1161/STR.0000000000000158. [PMID] 29367334.
2018
A Comparison of Pathophysiology in Humans and Rodent Models of Subarachnoid Hemorrhage.
Frontiers in molecular neuroscience. 11 [DOI] 10.3389/fnmol.2018.00071. [PMID] 29623028.
2018
AHA/ASA 2018 AIS guidelines: impact and opportunity for endovascular stroke care.
Journal of neurointerventional surgery. 10(9):813-817 [DOI] 10.1136/neurintsurg-2018-013911. [PMID] 29807886.
2018
Angiographic and clinical outcomes of balloon remodeling versus unassisted coil embolization in the ruptured aneurysm cohort of the GEL THE NEC study.
Journal of neurointerventional surgery. 10(5):446-450 [DOI] 10.1136/neurintsurg-2017-013326. [PMID] 28821627.
2018
Cost Analysis of Endovascular Coiling and Surgical Clipping for the Treatment of Ruptured Intracranial Aneurysms.
World neurosurgery. [DOI] 10.1016/j.wneu.2018.12.028. [PMID] 30579007.
2018
Estrogen Deficiency Promotes Cerebral Aneurysm Rupture by Upregulation of Th17 Cells and Interleukin-17A Which Downregulates E-Cadherin.
Journal of the American Heart Association. 7(8) [DOI] 10.1161/JAHA.118.008863. [PMID] 29654199.
2018
Introducing a Novel Method of Intravascular Adeno-associated Virus-mediated Gene Delivery.
Virology (Hyderabad). 2(1) [PMID] 30498814.
2018
Laboratory assessments of therapeutic platelet inhibition in endovascular neurosurgery: comparing results of the VerifyNow P2Y12 assay to thromboelastography with platelet mapping
Journal of Neurosurgery. 129(5):1160-1165 [DOI] 10.3171/2017.6.JNS17535. [PMID] 29271717.
2018
Local Delivery Is Critical for Monocyte Chemotactic Protein-1 Mediated Site-Specific Murine Aneurysm Healing.
Frontiers in neurology. 9 [DOI] 10.3389/fneur.2018.00158. [PMID] 29615957.
2018
M1 macrophages are required for murine cerebral aneurysm formation.
Journal of neurointerventional surgery. 10(1):93-97 [DOI] 10.1136/neurintsurg-2016-012911. [PMID] 28196918.
2018
Outcomes After Off-Label Use of the Pipeline Embolization Device for Intracranial Aneurysms: A Multicenter Cohort Study.
World neurosurgery. 115:e200-e205 [DOI] 10.1016/j.wneu.2018.04.012. [PMID] 29679782.
2018
Temporal cascade of inflammatory cytokines and cell-type populations in monocyte chemotactic protein-1 (MCP-1)-mediated aneurysm healing.
Journal of neurointerventional surgery. 10(3):301-305 [DOI] 10.1136/neurintsurg-2017-013063. [PMID] 28450456.
2018
The Patient Size Setting: A Novel Dose Reduction Strategy in Cerebral Endovascular Neurosurgery Using Biplane Fluoroscopy.
World neurosurgery. 110:e636-e641 [DOI] 10.1016/j.wneu.2017.11.056. [PMID] 29180081.
2018
Thrombolysis is an Independent Risk Factor for Poor Outcome After Carotid Revascularization.
Neurosurgery. 83(5):922-930 [DOI] 10.1093/neuros/nyx551. [PMID] 29136204.
2018
Validation of a neurovascular comorbidities index for retrospective database analysis.
Journal of neurosurgery. 130(1):273-277 [DOI] 10.3171/2017.8.JNS171413. [PMID] 29372882.
2017
Editorial. Initial experience with PulseRider treatment for wide-necked bifurcation aneurysms.
Journal of neurosurgery. 127(1):59-60 [DOI] 10.3171/2016.3.JNS16412. [PMID] 27689456.
2017
Hydrogel versus Bare Platinum Coils in Patients with Large or Recurrent Aneurysms Prone to Recurrence after Endovascular Treatment: A Randomized Controlled Trial
American Journal of Neuroradiology. 38(3):432-441 [DOI] 10.3174/ajnr.a5101.
2017
Management of Septic emboli in patients with infectious endocarditis.
Journal of cardiac surgery. 32(5):274-280 [DOI] 10.1111/jocs.13129. [PMID] 28417489.
2017
Monocyte Chemotactic Protein-1-Interleukin-6-Osteopontin Pathway of Intra-Aneurysmal Tissue Healing.
Stroke. 48(4):1052-1060 [DOI] 10.1161/STROKEAHA.116.015590. [PMID] 28292871.
2017
Procedural Requirements and Certification Paradigms for Stroke Care Delivery: Perspective of Neurointerventional Professional Societies.
Stroke. 48(10):2901-2904 [DOI] 10.1161/STROKEAHA.117.016773. [PMID] 28916668.
2017
Randomized, Open-Label, Phase 1/2a Study to Determine the Maximum Tolerated Dose of Intraventricular Sustained Release Nimodipine for Subarachnoid Hemorrhage (NEWTON [Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage]).
Stroke. 48(1):145-151 [DOI] 10.1161/STROKEAHA.116.014250. [PMID] 27932607.
2017
Role of Interleukin-10 in Acute Brain Injuries.
Frontiers in neurology. 8 [DOI] 10.3389/fneur.2017.00244. [PMID] 28659854.
2017
Training Standards in Neuroendovascular Surgery: Program Accreditation and Practitioner Certification.
Stroke. 48(8):2318-2325 [DOI] 10.1161/STROKEAHA.117.016560. [PMID] 28706116.
2016
A new comorbidities index for risk stratification for treatment of unruptured cerebral aneurysms.
Journal of neurosurgery. 125(3):713-9 [DOI] 10.3171/2015.8.JNS14553. [PMID] 26745486.
2016
Establishing standard hospital performance measures for cervical spinal trauma: a Nationwide In-patient Sample study.
Spinal cord. 54(4):306-13 [DOI] 10.1038/sc.2015.185. [PMID] 26481701.
2016
Factors Associated With Recurrent Ischemic Stroke in the Medical Group of the SAMMPRIS Trial.
JAMA neurology. 73(3):308-15 [DOI] 10.1001/jamaneurol.2015.4315. [PMID] 26747792.
2016
Flow Diversion for All Middle Cerebral Artery Aneurysms-Are We There Yet?
World neurosurgery. 90:617-618 [DOI] 10.1016/j.wneu.2015.12.021. [PMID] 26723295.
2016
National treatment practices in the management of infectious intracranial aneurysms and infective endocarditis.
Journal of neurointerventional surgery. 8(7):741-6 [DOI] 10.1136/neurintsurg-2015-011834. [PMID] 26044986.
2016
Onyx extrusion through the scalp after embolization of dural arteriovenous fistula.
Journal of neurointerventional surgery. 8(9) [DOI] 10.1136/neurintsurg-2015-011879.rep. [PMID] 26232437.
2016
Rapid, spontaneous obliteration of intracranial arteriovenous malformation.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 34:210-213 [DOI] 10.1016/j.jocn.2016.05.027. [PMID] 27473023.
2015
2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the Early Management of Patients With Acute Ischemic Stroke Regarding Endovascular Treatment: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.
Stroke. 46(10):3020-35 [DOI] 10.1161/STR.0000000000000074. [PMID] 26123479.
2015
Flow Diversion Technologies in Evolution: A Review of the First Two Generations of Flow Diversion Devices.
World neurosurgery. 84(2):254-6 [DOI] 10.1016/j.wneu.2015.03.010. [PMID] 25827045.
2015
Health disparities and stroke: the influence of insurance status on the prevalence of patient safety indicators and hospital-acquired conditions.
Journal of neurosurgery. 122(4):870-5 [DOI] 10.3171/2014.12.JNS14646. [PMID] 25658779.
2015
MR CLEAN: past the tipping point of clinical equipoise.
Journal of neurosurgery. 123(1):101-2 [DOI] 10.3171/2015.2.JNS15284. [PMID] 25823373.
2015
NEWTON: Nimodipine Microparticles to Enhance Recovery While Reducing Toxicity After Subarachnoid Hemorrhage.
Neurocritical care. 23(2):274-84 [DOI] 10.1007/s12028-015-0112-2. [PMID] 25678453.
2015
Onyx extrusion through the scalp after embolization of dural arteriovenous fistula.
BMJ case reports. 2015 [DOI] 10.1136/bcr-2015-011879. [PMID] 26220981.
2015
Return of visual function after bilateral visual loss following flow diversion embolization of a giant ophthalmic aneurysm due to both reduction in mass effect and reduction in aneurysm pulsation.
Journal of neurointerventional surgery. 7(1) [DOI] 10.1136/neurintsurg-2013-010960.rep. [PMID] 24452961.
2015
The Comparative Effectiveness of Specific Professional Educational Tools for Correcting Knowledge Gaps Among Practicing Neurosurgeons.
Neurosurgery. 62 Suppl 1:133-6 [DOI] 10.1227/NEU.0000000000000783. [PMID] 26181932.
2015
The safety of vasopressor-induced hypertension in subarachnoid hemorrhage patients with coexisting unruptured, unprotected intracranial aneurysms.
Journal of neurosurgery. 123(4):862-71 [DOI] 10.3171/2014.12.JNS141201. [PMID] 26207606.
2015
Validation of a System to Predict Recanalization After Endovascular Treatment of Intracranial Aneurysms.
Neurosurgery. 77(2):168-73; discussion 173 [DOI] 10.1227/NEU.0000000000000744. [PMID] 25850603.
2014
A rose by any other name: eponyms and neurosurgery.
World neurosurgery. 81(1):77-9 [DOI] 10.1016/j.wneu.2013.02.049. [PMID] 23416776.
2014
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
Lancet (London, England). 383(9914):333-41 [DOI] 10.1016/S0140-6736(13)62038-3. [PMID] 24168957.
2014
Aggressive surgical management of dural venous sinus thrombosis: a review of the literature.
World neurosurgery. 82(1-2):e61-3 [DOI] 10.1016/j.wneu.2013.01.075. [PMID] 23333987.
2014
Aneurysm Healing By Cytokine-Releasing Endovascular Coil: Inflammation and Vascular Repair
Angiogenesis. 17(1):306-307
2014
Endovascular and Surgical Treatment of Unruptured MCA Aneurysms: Meta-Analysis and Review of the Literature.
Stroke research and treatment. 2014 [DOI] 10.1155/2014/348147. [PMID] 24800103.
2014
Endovascular management of recurrent aneurysms.
Neurological research. 36(4):323-31 [DOI] 10.1179/1743132814Y.0000000325. [PMID] 24617933.
2014
Fighting fire with fire: the revival of thermotherapy for gliomas.
Anticancer research. 34(2):565-74 [PMID] 24510985.
2014
Flow diversion technologies in evolution: a review of the first 4 generations of flow diversion devices.
World neurosurgery. 81(3-4):452-3 [DOI] 10.1016/j.wneu.2014.01.008. [PMID] 24456827.
2014
Flow re-direction endoluminal device.
Journal of neurosurgery. 120(5):1156-7; discussion 1157 [DOI] 10.3171/2013.10.JNS132023. [PMID] 24628612.
2014
Inflammation and cerebral aneurysms.
Translational stroke research. 5(2):190-8 [DOI] 10.1007/s12975-013-0313-y. [PMID] 24323732.
2014
Introduction: Endovascular neurosurgery video supplement.
Neurosurgical focus. 37(1 Suppl) [DOI] 10.3171/2014.V2.FOCUSIntro. [PMID] 24983734.
2014
Ipsilateral cerebral hemorrhage following deployment of the Pipeline Embolization Device.
Journal of neurosurgery. 120(2):363-4 [DOI] 10.3171/2013.10.JNS132111. [PMID] 24320026.
2014
Modified murine intracranial aneurysm model: aneurysm formation and rupture by elastase and hypertension.
Journal of neurointerventional surgery. 6(6):474-9 [DOI] 10.1136/neurintsurg-2013-010788. [PMID] 23943816.
2014
Moniz to modern day magnetic resonance/computed tomographic angiography: the evolution of carotid nomenclature.
World neurosurgery. 82(3-4):320-1 [DOI] 10.1016/j.wneu.2013.10.015. [PMID] 24121295.
2014
Novel high-throughput in vitro model for identifying hemodynamic-induced inflammatory mediators of cerebral aneurysm formation.
Hypertension (Dallas, Tex. : 1979). 64(6):1306-13 [DOI] 10.1161/HYPERTENSIONAHA.114.03775. [PMID] 25225207.
2014
Patients prone to recurrence after endovascular treatment: periprocedural results of the PRET randomized trial on large and recurrent aneurysms.
AJNR. American journal of neuroradiology. 35(9):1667-76 [DOI] 10.3174/ajnr.A4035. [PMID] 24948508.
2014
Preconditioning effect on cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage.
Neurosurgery. 74(4):351-8; discussion 358 [DOI] 10.1227/NEU.0000000000000282. [PMID] 24378827.
2014
Race and income disparity in ischemic stroke care: nationwide inpatient sample database, 2002 to 2008.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 23(1):17-24 [DOI] 10.1016/j.jstrokecerebrovasdis.2012.06.004. [PMID] 22818388.
2014
Return of visual function after bilateral visual loss following flow diversion embolization of a giant ophthalmic aneurysm due to both reduction in mass effect and reduction in aneurysm pulsation.
BMJ case reports. 2014 [DOI] 10.1136/bcr-2013-010960. [PMID] 24414181.
2014
Stent-assisted coil embolization.
Journal of neurosurgery. 121(1):1-2 [DOI] 10.3171/2013.11.JNS132203. [PMID] 24834946.
2014
Stromal Cell Derived Factor-1 Promoted Angiogenesis and Inflammatory Cell Infiltration in Aneurysm Walls
Journal of Neurosurgery. 120(1):73-86 [DOI] 10.3171/2013.9.JNS122074. [PMID] 24160472.
2014
The debate over eponyms.
Clinical anatomy (New York, N.Y.). 27(8):1137-40 [DOI] 10.1002/ca.22409. [PMID] 24760487.
2014
Vasospasm in aneurysmal subarachnoid hemorrhage.
World neurosurgery. 82(3-4):250-2 [DOI] 10.1016/j.wneu.2014.06.048. [PMID] 24984246.
2013
A multicenter study of stent-assisted coiling of cerebral aneurysms with a Y configuration.
Neurosurgery. 73(3):466-72 [DOI] 10.1227/NEU.0000000000000015. [PMID] 23756744.
2013
An updated definition of stroke for the 21st century: a statement for healthcare professionals from the American Heart Association/American Stroke Association.
Stroke. 44(7):2064-89 [DOI] 10.1161/STR.0b013e318296aeca. [PMID] 23652265.
2013
Angioplasty alone versus angioplasty and stenting for acute cervical carotid occlusions: technical and antiplatelet considerations.
World neurosurgery. 79(1):66-8 [DOI] 10.1016/j.wneu.2012.10.040. [PMID] 23103275.
2013
Can we rebuild the human brain? The exciting promise and early evidence that stem cells may provide a real clinical cure for stroke in humans.
World neurosurgery. 80(5):e69-72 [DOI] 10.1016/j.wneu.2012.07.012. [PMID] 22846654.
2013
Cerebral aneurysms in pregnancy and delivery: pregnancy and delivery do not increase the risk of aneurysm rupture.
Neurosurgery. 72(2):143-9; discussion 150 [DOI] 10.1227/NEU.0b013e3182796af9. [PMID] 23147786.
2013
Concomitant intracranial pressure monitoring during venous sinus stenting for intracranial hypertension secondary to venous sinus stenosis.
Journal of neurointerventional surgery. 5(4) [DOI] 10.1136/neurintsurg-2012-010371. [PMID] 22738775.
2013
Endothelin-1 induced middle cerebral artery occlusion model for ischemic stroke with laser Doppler flowmetry guidance in rat.
Journal of visualized experiments : JoVE. (72) [DOI] 10.3791/50014. [PMID] 23438950.
2013
Enhanced staff communication and reduced near-miss errors with a neurointerventional procedural checklist.
Journal of neurointerventional surgery. 5(5):497-500 [DOI] 10.1136/neurintsurg-2012-010430. [PMID] 22773334.
2013
Establishing standard performance measures for adult brain tumor patients: a Nationwide Inpatient Sample database study.
Neuro-oncology. 15(11):1580-8 [DOI] 10.1093/neuonc/not108. [PMID] 24084409.
2013
Establishing standard performance measures for adult stroke patients: a nationwide inpatient sample database study.
World neurosurgery. 80(6):699-708.e2 [DOI] 10.1016/j.wneu.2013.08.024. [PMID] 23994132.
2013
Flow failure from intracranial atherosclerotic disease: a rationale for endovascular intervention in a population with recurrent symptoms despite maximal medical therapy.
Journal of neurointerventional surgery. 5(4) [DOI] 10.1136/neurintsurg-2012-010275. [PMID] 22661599.
2013
In reply.
Neurosurgery. 72(1) [DOI] 10.1227/NEU.0b013e31827529bd. [PMID] 23037826.
2013
Occurrence of angiographic femoral artery complications after vascular closure with Mynx and AngioSeal.
Journal of neurointerventional surgery. 5(2):161-4 [DOI] 10.1136/neurintsurg-2011-010217. [PMID] 22266794.
2013
Prevalence of patient safety indicators and hospital-acquired conditions in those treated for unruptured cerebral aneurysms: establishing standard performance measures using the Nationwide Inpatient Sample database.
Journal of neurosurgery. 119(4):966-73 [DOI] 10.3171/2013.5.JNS122378. [PMID] 23746098.
2013
Rationale for treating unruptured intracranial aneurysms: actuarial analysis of natural history risk versus treatment risk for coiling or clipping based on 14,050 patients in the Nationwide Inpatient Sample database.
World neurosurgery. 79(3-4):472-8 [DOI] 10.1016/j.wneu.2012.01.038. [PMID] 22381870.
2013
Review of cerebral aneurysm formation, growth, and rupture.
Stroke. 44(12):3613-22 [DOI] 10.1161/STROKEAHA.113.002390. [PMID] 24130141.
2013
Risk factors, incidence, and effect of cardiac failure and myocardial infarction in aneurysmal subarachnoid hemorrhage patients.
Neurosurgery. 73(3):450-7; quiz 457 [DOI] 10.1227/NEU.0000000000000001. [PMID] 23728449.
2013
Shifting paradigms of endovascular therapies for cavernous carotid fistulas.
World neurosurgery. 80(5):484-6 [DOI] 10.1016/j.wneu.2013.03.051. [PMID] 23541753.
2013
The prevalence of patient safety indicators and hospital-acquired conditions in patients with ruptured cerebral aneurysms: establishing standard performance measures using the Nationwide Inpatient Sample database.
Journal of neurosurgery. 119(6):1633-40 [DOI] 10.3171/2013.7.JNS13595. [PMID] 23991899.
2013
The stent anchor technique for distal access through a large or giant aneurysm.
Journal of neurointerventional surgery. 5(4) [DOI] 10.1136/neurintsurg-2012-010276. [PMID] 22544820.
2012
A novel tissue engineering approach using an endothelial progenitor cell-seeded biopolymer to treat intracranial saccular aneurysms.
Journal of neurosurgery. 117(3):546-54 [DOI] 10.3171/2012.5.JNS091308. [PMID] 22746379.
2012
Axium MicroFX coil for the completing endovascular aneurysm surgery study (ACCESS). A prospective evaluation of the safety and durability of Axium MicroFX PGLA coils.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences. 18(2):200-7 [PMID] 22681737.
2012
Comment.
Neurosurgery. 71(4) [PMID] 23162841.
2012
Comments.
Neurosurgery. 71(1) [PMID] 25853156.
2012
Computed tomographic perfusion imaging of non-hemorrhagic cerebral hyperperfusion syndrome and reversal following medical treatment after carotid artery angioplasty and stenting.
Journal of neurointerventional surgery. 4(3) [DOI] 10.1136/jnis.2010.003558. [PMID] 21990434.
2012
Cross-circulation techniques for endovascular revascularization of acute stroke.
World neurosurgery. 77(2):300-1 [DOI] 10.1016/j.wneu.2011.06.011. [PMID] 22120365.
2012
Delayed intraparenchymal hemorrhage following pipeline embolization device treatment for a giant recanalized ophthalmic aneurysm.
Journal of neurointerventional surgery. 4(5) [DOI] 10.1136/neurintsurg-2011-010129. [PMID] 21990545.
2012
Detailed analysis of periprocedural strokes in patients undergoing intracranial stenting in Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS).
Stroke. 43(10):2682-8 [PMID] 22984008.
2012
Direct radial artery access with the 070 neuron guide catheter for aneurysm coiling: a novel application of the neuron catheter for cerebral interventions.
Neurosurgery. 71(2 Suppl Operative):onsE329-34; discussion onsE334 [DOI] 10.1227/NEU.0b013e318265a454. [PMID] 22743361.
2012
Direct thrombectomy using the Penumbra thromboaspiration catheter for the treatment of cerebral venous sinus thrombosis.
World neurosurgery. 77(3-4):591.e15-8 [DOI] 10.1016/j.wneu.2011.02.020. [PMID] 22120408.
2012
Endovascular Intervention for Acute Stroke Due To Infective Endocarditis: a Case Report
. 78
2012
Guidelines for the management of aneurysmal subarachnoid hemorrhage: a guideline for healthcare professionals from the American Heart Association/american Stroke Association.
Stroke. 43(6):1711-37 [DOI] 10.1161/STR.0b013e3182587839. [PMID] 22556195.
2012
Higher complications and no improvement in mortality in the ACGME resident duty-hour restriction era: an analysis of more than 107,000 neurosurgical trauma patients in the Nationwide Inpatient Sample database.
Neurosurgery. 70(6):1369-81; discussion 1381 [DOI] 10.1227/NEU.0b013e3182486a75. [PMID] 22227483.
2012
Impending federal cuts in graduate medical education funding: an urgent threat to neurosurgery training and manpower.
World neurosurgery. 77(5-6):597-9 [DOI] 10.1016/j.wneu.2012.03.004. [PMID] 22430323.
2012
Intentional partial coiling dome protection of complex ruptured cerebral aneurysms prevents acute rebleeding and produces favorable clinical outcomes.
Acta neurochirurgica. 154(1):27-31 [DOI] 10.1007/s00701-011-1214-z. [PMID] 22068717.
2012
Long-term results of enterprise stent-assisted coiling of cerebral aneurysms.
Neurosurgery. 71(2):239-44; discussion 244 [DOI] 10.1227/NEU.0b013e3182571953. [PMID] 22472556.
2012
Management of tandem occlusion stroke with endovascular therapy.
Neurosurgical focus. 32(5) [DOI] 10.3171/2012.1.FOCUS11350. [PMID] 22537125.
2012
Nonaneurysmal subarachnoid hemorrhage: an update.
Current atherosclerosis reports. 14(4):328-34 [DOI] 10.1007/s11883-012-0256-x. [PMID] 22638876.
2012
Perioperative safety of Hydrosoft coils.
Journal of neurointerventional surgery. 4(5):375-8 [DOI] 10.1136/neurintsurg-2011-010106. [PMID] 21990538.
2012
Review of reported complications associated with the Pipeline Embolization Device.
World neurosurgery. 77(3-4):403-4 [DOI] 10.1016/j.wneu.2012.02.038. [PMID] 22360865.
2012
Role of Mean Transit Time (Mtt) Perfusion Map On the Aquilion One Ct Scanner Using Svd Plus Algorithm in Acute Stroke
. 78
2012
Takayasu’s arteritis: Is it a reversible disease? Case Report and Literature Review.
Surgical neurology international. 3 [DOI] 10.4103/2152-7806.102947. [PMID] 23227437.
2012
The “July phenomenon” for neurosurgical mortality and complications in teaching hospitals: an analysis of more than 850,000 neurosurgical patients in the nationwide inpatient sample database, 1998 to 2008.
Neurosurgery. 71(3):562-71; discussion 571 [DOI] 10.1227/NEU.0b013e31825ea51b. [PMID] 22592329.
2012
The future of glioma treatment: stem cells, nanotechnology and personalized medicine.
Future oncology (London, England). 8(9):1149-56 [DOI] 10.2217/fon.12.111. [PMID] 23030489.
2012
The Orbit Galaxy XTRASOFT Coils: A Multicenter Study of Coil Safety and Efficacy in Both Ruptured and Unruptured Cerebral Aneurysms.
Journal of vascular and interventional neurology. 5(1):17-21 [PMID] 22737261.
2011
A prospective randomized single-blind trial of patient comfort following vessel closure: extravascular synthetic sealant closure provides less pain than a self-tightening suture vascular compression device.
Journal of neurointerventional surgery. 3(3):219-23 [DOI] 10.1136/jnis.2010.003988. [PMID] 21990828.
2011
A simple technique for morphological measurement of cerebral arterial circle variations using public domain software (Osiris).
Anatomy & cell biology. 44(4):324-30 [DOI] 10.5115/acb.2011.44.4.324. [PMID] 22254161.
2011
ACR Appropriateness Criteria® on cerebrovascular disease.
Journal of the American College of Radiology : JACR. 8(8):532-8 [DOI] 10.1016/j.jacr.2011.05.010. [PMID] 21807345.
2011
Aggressive intervention to treat a young woman with intracranial hemorrhage following unsuccessful intravenous thrombolysis for left middle cerebral artery occlusion. Case report.
Journal of neurosurgery. 115(2):359-63 [DOI] 10.3171/2011.3.JNS101514. [PMID] 21495825.
2011
Avastin in the treatment for radiation necrosis: exciting results from a recent randomized trial.
World neurosurgery. 75(1):4-5 [DOI] 10.1016/j.wneu.2011.01.012. [PMID] 21492640.
2011
Critical care guidelines on the endovascular management of cerebral vasospasm.
Neurocritical care. 15(2):336-41 [DOI] 10.1007/s12028-011-9600-1. [PMID] 21761272.
2011
Critical care management of patients following aneurysmal subarachnoid hemorrhage: recommendations from the Neurocritical Care Society’s Multidisciplinary Consensus Conference.
Neurocritical care. 15(2):211-40 [DOI] 10.1007/s12028-011-9605-9. [PMID] 21773873.
2011
Delayed complication from a percutaneous vascular closure device following a neuro-interventional procedure.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences. 17(4):495-500 [PMID] 22192557.
2011
Delayed thrombosis or stenosis following enterprise-assisted stent-coiling: is it safe? Midterm results of the interstate collaboration of enterprise stent coiling.
Neurosurgery. 69(4):908-13; discussion 913 [DOI] 10.1227/NEU.0b013e318228490c. [PMID] 21670718.
2011
Effect of Weekend Compared To Weekday Stroke Admission On Thrombolytic Use, In-Hospital Mortality, Discharge Disposition, Hospital Charges, and Length of Stay in the Nationwide Inpatient Sample Database: 2002-2007
. 42
2011
Glioblastoma multiforme tumor stem cells form endothelium.
World neurosurgery. 75(3-4):338-9 [DOI] 10.1016/j.wneu.2011.02.038. [PMID] 21600458.
2011
Impact of intracranial self-expanding stents in the treatment of acute ischemic stroke: efficacy and limitations.
Journal of neurointerventional surgery. 3(4):364-8 [DOI] 10.1136/jnis.2011.004614. [PMID] 21990463.
2011
Incidence of seizures or epilepsy after clipping or coiling of ruptured and unruptured cerebral aneurysms in the nationwide inpatient sample database: 2002-2007.
Neurosurgery. 69(3):644-50; discussion 650 [DOI] 10.1227/NEU.0b013e31821bc46d. [PMID] 21499155.
2011
Incidence of ventricular shunt placement for hydrocephalus with clipping versus coiling for ruptured and unruptured cerebral aneurysms in the Nationwide Inpatient Sample database: 2002 to 2007.
World neurosurgery. 76(6):548-54 [DOI] 10.1016/j.wneu.2011.05.054. [PMID] 22251503.
2011
Interventional neurovascular disease: avoidance and management of complications and review of the current literature.
Journal of neurosurgical sciences. 55(3):233-42 [PMID] 21968586.
2011
Intracranial stents for treatment of acute ischemic stroke: evolution and current status.
World neurosurgery. 76(6 Suppl):S24-34 [DOI] 10.1016/j.wneu.2011.02.031. [PMID] 22182268.
2011
Monocyte chemotactic protein-1 promotes inflammatory vascular repair of murine carotid aneurysms via a macrophage inflammatory protein-1α and macrophage inflammatory protein-2-dependent pathway.
Circulation. 124(20):2243-52 [DOI] 10.1161/CIRCULATIONAHA.111.036061. [PMID] 22007074.
2011
Rebleeding risk after treatment of ruptured intracranial aneurysms.
Journal of neurosurgery. 114(6):1778-84 [DOI] 10.3171/2011.1.JNS101232. [PMID] 21332293.
2011
Recanalization therapy for acute ischemic stroke, part 1: surgical embolectomy and chemical thrombolysis.
Neurosurgical review. 34(1):1-9 [DOI] 10.1007/s10143-010-0293-2. [PMID] 21107631.
2011
Recanalization therapy for acute ischemic stroke, part 2: mechanical intra-arterial technologies.
Neurosurgical review. 34(1):11-20 [DOI] 10.1007/s10143-010-0294-1. [PMID] 21107630.
2011
Serum Sdf1-a Levels Significantly Increase Following Stroke and Are Associated With Increased Hematopoetic Stem Cell Mobilization
. 42:E253-E254
2011
Stent-associated flow remodeling causes further occlusion of incompletely coiled aneurysms.
Neurosurgery. 69(3):598-603; discussion 603 [DOI] 10.1227/NEU.0b013e3182181c2b. [PMID] 21430583.
2011
Stenting versus aggressive medical therapy for intracranial arterial stenosis.
The New England journal of medicine. 365(11):993-1003 [DOI] 10.1056/NEJMoa1105335. [PMID] 21899409.
2011
The Novel Trkb Agonist, 7,8-Dihydroxyflavone Enhances Stem Cell Mobilization After Stroke
. 42
2011
Tissue Plasminogen Activator Impairs Hematopoietic Stem Cell Function, Thus Potentially Limiting Stroke Recovery
. 42
2011
Unruptured cerebral aneurysms do not shrink when they rupture: multicenter collaborative aneurysm study group.
Neurosurgery. 68(1):155-60; discussion 160 [DOI] 10.1227/NEU.0b013e3181ff357c. [PMID] 21150760.
2011
Vasospasm after aneurysmal subarachnoid hemorrhage: review of randomized controlled trials and meta-analyses in the literature.
World neurosurgery. 76(5):446-54 [DOI] 10.1016/j.wneu.2011.02.030. [PMID] 22152574.
2010
A novel murine elastase saccular aneurysm model for studying bone marrow progenitor-derived cell-mediated processes in aneurysm formation.
Neurosurgery. 66(3):544-50; discussion 550 [DOI] 10.1227/01.NEU.0000365616.46414.2B. [PMID] 20173550.
2010
Acute intraprocedural thrombus formation during wingspan intracranial stent placement for intracranial atherosclerotic disease.
Neurosurgery. 67(3 Suppl Operative):ons166-70; discussion ons170 [DOI] 10.1227/01.NEU.0000380948.85926.3C. [PMID] 20679932.
2010
Clipping versus coiling for ruptured intracranial aneurysms: integrated medical learning at CNS 2007.
Neurosurgery. 66(1):19-34; discussion 34 [DOI] 10.1227/01.NEU.0000362005.93515.5B. [PMID] 19935437.
2010
Clipping versus coiling: the total hospital cost of aneurysm treatment.
World neurosurgery. 73(5):430-1 [DOI] 10.1016/j.wneu.2010.05.024. [PMID] 20920915.
2010
Effect of weekend compared with weekday stroke admission on thrombolytic use, in-hospital mortality, discharge disposition, hospital charges, and length of stay in the Nationwide Inpatient Sample Database, 2002 to 2007.
Stroke. 41(10):2323-8 [DOI] 10.1161/STROKEAHA.110.591081. [PMID] 20724715.
2010
Length of stay and total hospital charges of clipping versus coiling for ruptured and unruptured adult cerebral aneurysms in the Nationwide Inpatient Sample database 2002 to 2006.
Stroke. 41(2):337-42 [DOI] 10.1161/STROKEAHA.109.569269. [PMID] 20044522.
2010
Preliminary observation on predicting the need for coil extraction during microsurgery: the clip-coil ratio.
Acta neurochirurgica. 152(3):431-4 [PMID] 20213931.
2010
Primary intracranial stenting in acute ischemic stroke.
Current cardiology reports. 12(1):14-9 [DOI] 10.1007/s11886-009-0069-x. [PMID] 20425179.
2010
Promising new aneurysm occlusion and clinical outcome results from CCT and HELPS.
World neurosurgery. 74(4-5):389-90 [DOI] 10.1016/j.wneu.2010.10.011. [PMID] 21492575.
2010
Size ratio correlates with intracranial aneurysm rupture status: a prospective study.
Stroke. 41(5):916-20 [DOI] 10.1161/STROKEAHA.109.574244. [PMID] 20378866.
2010
Timing of aneurysm surgery: the International Cooperative Study revisited in the era of endovascular coiling.
Journal of neurointerventional surgery. 2(2):131-4 [DOI] 10.1136/jnis.2009.001172. [PMID] 21990592.
2009
Clinical course of nontraumatic, nonaneurysmal subarachnoid hemorrhage: a single-institution experience.
Neurosurgical focus. 26(5) [DOI] 10.3171/2009.2.FOCUS092. [PMID] 19409000.
2009
Direct thrombolysis for cerebral venous sinus thrombosis.
Neurosurgical focus. 27(5) [DOI] 10.3171/2009.7.FOCUS09146. [PMID] 19877797.
2009
Endoscopic-Assisted Resection of a Recurrent Juvenile Nasopharyngeal Angiofibroma (Jna) With Contributions From the Internal Carotid Artery
The Laryngoscope. 119(S1):S149-S149 [DOI] 10.1002/lary.20467.
2009
Factors associated with aspirin resistance in patients premedicated with aspirin and clopidogrel for endovascular neurosurgery.
Neurosurgery. 64(5):890-5; discussion 895 [DOI] 10.1227/01.NEU.0000341904.39691.2F. [PMID] 19287328.
2009
Modern treatment of cerebral metastases: Integrated Medical Learning(SM) at CNS 2007.
Journal of neuro-oncology. 93(1):89-105 [DOI] 10.1007/s11060-009-9833-4. [PMID] 19430885.
2009
Novel application of an intermediate sized bridging catheter as an adjunct to aneurysm coiling in patients with tortuous vasculature.
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences. 15(4):448-52 [PMID] 20465884.
2009
Shape memory alloys: metallurgy, biocompatibility, and biomechanics for neurosurgical applications.
Neurosurgery. 64(5 Suppl 2):199-214; discussion 214 [DOI] 10.1227/01.NEU.0000330392.09889.99. [PMID] 19404101.
2009
The effect of coiling versus clipping of ruptured and unruptured cerebral aneurysms on length of stay, hospital cost, hospital reimbursement, and surgeon reimbursement at the university of Florida.
Neurosurgery. 64(4):614-9; discussion 619 [DOI] 10.1227/01.NEU.0000340784.75352.A4. [PMID] 19197221.
2009
The Effect of Coiling Versus Clipping of Ruptured and Unruptured Cerebral Aneurysms On Length of Stay, Hospital Costs, Hospital Reimbursement, and Surgeon Reimbursement At a Southeast United States Academic Neurovascular Center
. 40:E167-E168
2009
The Treatment of Vein of Galen Malformations At Uf: a Combination of Historic and Modern Modalities
. 40
2009
Treatment of intracranial aneurysms with the Enterprise stent: a multicenter registry.
Journal of neurosurgery. 110(1):35-9 [DOI] 10.3171/2008.7.JNS08322. [PMID] 18976057.
2008
Comparison of N-Butyl Cyanoacrylate and Onyx for the Embolization of Intracranial Arteriovenous Malformations: Analysis of Fluoroscopy and Procedure Times
Neurosurgery. 63(1):73-78 [DOI] 10.1227/01.NEU.0000320136.05677.91.
2008
Comparison of N-butyl cyanoacrylate and onyx for the embolization of intracranial arteriovenous malformations: analysis of fluoroscopy and procedure times.
Neurosurgery. 63(1 Suppl 1):ONS73-8; discussion ONS78 [DOI] 10.1227/01.neu.0000335015.83616.12. [PMID] 18728607.
2008
Limitations of Diffusion-Weighted Imaging in the Diagnosis of Postoperative Infections
Neurosurgery. 62:577-582 [DOI] 10.1227/01.NEU.0000297089.10744.55.
2008
Limitations of diffusion-weighted imaging in the diagnosis of postoperative infections.
Neurosurgery. 62(3):577-83; discussion 577 [DOI] 10.1227/01.NEU.0000311349.25281.BD. [PMID] 18301347.
2008
Lower Incidence of Reoperation With Longer Shunt Survival With Adult Ventriculoperitoneal Shunts Placed for Hemorrhage-Related Hydrocephalus
Neurosurgery. 63(1):70-74 [DOI] 10.1227/01.NEU.0000319527.34738.9D.
2008
Lower incidence of reoperation with longer shunt survival with adult ventriculoperitoneal shunts placed for hemorrhage-related hydrocephalus.
Neurosurgery. 63(1):70-4; discussion 74 [DOI] 10.1227/01.NEU.0000335072.32105.38. [PMID] 18728570.
2007
Bottleneck factor and height-width ratio: association with ruptured aneurysms in patients with multiple cerebral aneurysms.
Neurosurgery. 61(4):716-22; discussion 722 [PMID] 17986932.
2007
Comparison of ruptured vs unruptured aneurysms in recanalization after coil embolization.
Surgical neurology. 68(1):19-23 [PMID] 17586214.
2006
Complications of cerebral arteriovenous malformation embolization: multivariate analysis of predictive factors.
Neurosurgery. 58(4):602-11; discussion 602 [PMID] 16575323.
2006
First-pass quantitative CT perfusion identifies thresholds for salvageable penumbra in acute stroke patients treated with intra-arterial therapy.
AJNR. American journal of neuroradiology. 27(1):20-5 [PMID] 16418350.
2006
Outcomes for surgical and endovascular management of intracranial aneurysms using a comprehensive grading system.
Neurosurgery. 59(5):1037-42; discussion 1043 [PMID] 17143238.
2005
Aneurysmal Expansion Presenting as Facial Weakness: Case Report and Review of the Literature.
Neurosurgery. 56(1):E202-E205 [DOI] 10.1227/01.NEU.0000146211.62306.CD. [PMID] 28184849.
2005
Aneurysmal expansion presenting as facial weakness: case report and review of the literature.
Neurosurgery. 56(1) [PMID] 15617605.
2005
Endovascular treatment of cerebral vasospasm: transluminal balloon angioplasty, intra-arterial papaverine, and intra-arterial nicardipine.
Neurosurgery clinics of North America. 16(3):501-16, vi [PMID] 15990041.
2005
Heparin-induced thrombocytopenia Type II in subarachnoid hemorrhage patients: incidence and complications.
Neurosurgery. 57(2):243-8; discussion 243 [PMID] 16094152.
2005
Safety of heparinization for cerebral aneurysm coiling soon after external ventriculostomy drain placement.
Neurosurgery. 57(5):845-9; discussion 845 [PMID] 16284554.
2005
Spinal epidural abscess: clinical presentation, management, and outcome.
Surgical neurology. 63(4):364-71; discussion 371 [PMID] 15808726.
2004
A modified technique for using elastase to create saccular aneurysms in animals that histologically and hemodynamically resemble aneurysms in human.
Acta neurochirurgica. 146(7):705-11 [PMID] 15197614.
2004
Age-dependent differences in short-term outcome after surgical or endovascular treatment of unruptured intracranial aneurysms in the United States, 1996-2000.
Neurosurgery. 54(1):18-28; discussion 28 [PMID] 14683537.
2004
Balloon kyphoplasty for vertebral compression fracture using a unilateral balloon tamp via a uni-pedicular approach: technical note.
Pain physician. 7(1):111-4 [PMID] 16868622.
2004
Computed tomographic demonstrated infarcts after surgical and endovascular treatment of aneurysmal subarachnoid hemorrhage.
Acta neurochirurgica. 146(11):1177-83 [PMID] 15349755.
2004
Effect of clipping, craniotomy, or intravascular coiling on cerebral vasospasm and patient outcome after aneurysmal subarachnoid hemorrhage.
Neurosurgery. 55(4):779-86; discussion 786 [PMID] 15458586.
2004
Incidence of residual intracranial AVMs after surgical resection and efficacy of immediate surgical re-exploration.
Acta neurochirurgica. 146(1):1-7; discussion 7 [PMID] 14740259.
2004
Persistent nonfused segments of the basilar artery: longitudinal versus axial nonfusion.
AJNR. American journal of neuroradiology. 25(7):1194-6 [PMID] 15313708.
2004
Results of a prospective protocol of computed tomographic angiography in place of catheter angiography as the only diagnostic and pretreatment planning study for cerebral aneurysms by a combined neurovascular team.
Neurosurgery. 54(6):1329-40; discussion 1340 [PMID] 15157289.
2003
CT angiography before embolization for hemorrhage in head and neck cancer.
AJNR. American journal of neuroradiology. 24(1):140-2 [PMID] 12533343.
2003
Important factors for a combined neurovascular team to consider in selecting a treatment modality for patients with previously clipped residual and recurrent intracranial aneurysms.
Neurosurgery. 52(4):732-8; discussion 738 [PMID] 12657168.
2003
In-hospital morbidity and mortality after endovascular treatment of unruptured intracranial aneurysms in the United States, 1996-2000: effect of hospital and physician volume.
AJNR. American journal of neuroradiology. 24(7):1409-20 [PMID] 12917139.
2002
Clinical and radiographic outcome in the management of posterior circulation aneurysms by use of direct surgical or endovascular techniques.
Neurosurgery. 51(1):14-21; discussion 21 [PMID] 12182412.
2002
Results of multimodality treatment for 141 patients with brain arteriovenous malformations and seizures: factors associated with seizure incidence and seizure outcomes.
Neurosurgery. 51(2):303-9; discussion 309 [PMID] 12182768.
2002
Risk of hemorrhage from unsecured, unruptured aneurysms during and after hypertensive hypervolemic therapy.
Neurosurgery. 50(6):1207-11; discussion 1211 [PMID] 12015837.
2001
Combined surgical and endovascular techniques of flow alteration to treat fusiform and complex wide-necked intracranial aneurysms that are unsuitable for clipping or coil embolization.
Journal of neurosurgery. 95(1):24-35 [PMID] 11453395.
2001
Results after surgical and endovascular treatment of paraclinoid aneurysms by a combined neurovascular team.
Neurosurgery. 48(1):78-89; discussion 89 [PMID] 11152364.
2001
Surgical and endovascular flow disconnection of intracranial pial single-channel arteriovenous fistulae.
Neurosurgery. 49(6):1351-63; discussion 1363 [PMID] 11846934.
2000
Multimodality treatment of nongalenic arteriovenous malformations in pediatric patients.
Neurosurgery. 47(2):346-57; discussion 357 [PMID] 10942007.
1999
Targeted inhibition of intrinsic coagulation limits cerebral injury in stroke without increasing intracerebral hemorrhage.
The Journal of experimental medicine. 190(1):91-9 [PMID] 10429673.
1998
Reduced microvascular thrombosis and improved outcome in acute murine stroke by inhibiting GP IIb/IIIa receptor-mediated platelet aggregation.
The Journal of clinical investigation. 102(7):1301-10 [PMID] 9769322.
1998
Surgical management of high-grade intracranial dural arteriovenous fistulas: leptomeningeal venous disruption without nidus excision.
Neurosurgery. 42(4):796-804; discussion 804 [PMID] 9574644.
1997
Exacerbation of cerebral injury in mice that express the P-selectin gene: identification of P-selectin blockade as a new target for the treatment of stroke.
Circulation research. 81(3):304-10 [PMID] 9285631.
1997
Use of a spectrophotometric hemoglobin assay to objectively quantify intracerebral hemorrhage in mice.
Stroke. 28(11):2296-302 [PMID] 9368579.

Grants

Jul 2022 ACTIVE
Targeting IL-6 for Vasospasm Treatment following Subarachnoid Hemorrhage: the Microglia Response
Role: Other
Funding: American Asso of Neurological Surgeons
Nov 2021 ACTIVE
Investigator Initiated Research Support Agreement for Drug & Funding Provision
Role: Principal Investigator
Funding: JANSSEN SCIENTIFIC AFFAIRS via NATL INST OF HLTH NINDS
Nov 2021 ACTIVE
Microglial response to aneurysmal subarachnoid hemorrhage: Role of the NLRP3 inflammasome
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Sep 2021 ACTIVE
Comparison of Anti-coagulation and anti-Platelet Therapies for Intracranial Vascular Atherostenosis
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Nov 2020 – Jul 2021
Sequential?release?of?chemokines?from?coated?coils?to?target?aneurysm?healing
Role: Other
Funding: SOCIETY OF NEUROINTERVENTIONAL SURGERY
Nov 2020 – Oct 2021
Neutrophil Extracellular Trap Formation: A novel mechanism for intracranial aneurysm formation and rupture
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Nov 2020 – Oct 2021
NLRP3-mediated pyroptosis as a novel mechanism of cerebral aneurysm rupture
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Oct 2020 – Oct 2021
Neutrophil Infiltration in Coiled Aneurysm Healing: Adjuvant IL-17 Blockade
Role: Other
Funding: THE ANEURYSM AND AVM FOUNDATION
Oct 2020 ACTIVE
ADAPT: Adropin Regulation of DCI and CV in Patients with Aneurysmal Subarachnoid Hemorrhage (aSAH)
Role: Co-Investigator
Funding: UF FOUNDATION
May 2020 ACTIVE
Inflammatory Mediators and Mechanisms of Cerebral Aneurysm Formation and Rupture
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Apr 2020 – Oct 2020
FY20 NREF Fellowship Bardhi: IL-17 blockade on neutrophil recruitment in coiled aneurysm healing
Role: Principal Investigator
Funding: NEUROSURGERY RES AND EDU FOU
Oct 2019 – Sep 2021
Neutrophil Infiltration in Coiled Aneurysm Healing
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Oct 2019 – Sep 2021
NLRP3 as a Therapeutic Target in Intracranial Aneurysm Pathogenesis
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Jul 2019 ACTIVE
University of Florida R25 Early Research Program for Neurology and Neurosurgery Residents
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Jul 2019 ACTIVE
Inflammation and Cerebral Aneurysm Formation: Targets for Modulation and Vascular Repair
Role: Principal Investigator
Funding: UF FOUNDATION
Jul 2019 ACTIVE
Understanding aneurysm pathogenesis using a murine elastase-induced intracranial aneurysms model
Role: Principal Investigator
Funding: UF FOUNDATION
May 2019 – Apr 2020
Inflammatory Mediators and Mechanisms of Cerebral Aneurysm Formation and Rupture
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Oct 2018 – Sep 2019
Osteopontin-mediated Cerebral Aneurysm Healing: Th2 Cell Activation
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Oct 2017 – Sep 2018
Mechanism of Aneurysm Progression and Healing: Telomere and Telomerase Activity in Cerebral Aneurysm
Role: Other
Funding: BRAIN ANEURYSM FOU
Oct 2017 – Sep 2018
Studying IL-6 and IL-17 in the cerebral aneurysm development of VCD mice
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Sep 2016 – Sep 2017
The estrogen-deficiency-IL-17 pathway for cerebral aneurysm growth and rupture
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Aug 2016 – Jul 2019
Regulation and Implication of Hemoglobin Clearance in Subarachnoid Hemorrhagic Patients
Role: Co-Investigator
Funding: NATL INST OF HLTH NINDS
Oct 2015 – Sep 2016
Mechanism of aneurysm progression and healing: differential roles of macrophages in distinct phases of inflammation
Role: Principal Investigator
Funding: BRAIN ANEURYSM FOU
Jul 2015 – Jun 2016
2015-2016 Neuro Endovascular Surgery Fellowship
Role: Principal Investigator
Funding: CODMAN AND SHURTLEFF, INC
Jul 2015 – Jun 2016
Medtronic & Covidien Fellowship Grant
Role: Principal Investigator
Funding: MEDTRONIC INC
Feb 2014 – Jan 2019
Cerebral Aneurysm Healing: Cellular Mediators, Mechanisms and Downstream Actions
Role: Principal Investigator
Funding: NATL INST OF HLTH NINDS
Jun 2010 – Jun 2016
Support Professorship in Understanding Aneurysm Pathogenesis – Brian Hoh
Role: Principal Investigator
Funding: UF FOUNDATION
Feb 2009 ACTIVE
Wells Center for Brain Tumor Therapy
Role: Principal Investigator
Funding: UF FOUNDATION
Jul 2007 – Aug 2016
Clinical and Translational Science Institute
Role: Project Manager
Funding: UF RESEARCH FOU
Jan 2004 ACTIVE
Eblen Research Endowment # 011074
Role: Principal Investigator
Funding: UF FOUNDATION

Education

Residency – Neurological Surgery
2005 · Massachusetts General Hospital
Internship – Surgery
1999 · Massachusetts General Hospital

Contact Details

Phones:
Business:
(352) 273-9000
Emails:
Executive Assistant:
Addresses:
Business Mailing:
L2-100
PO BOX 100265
NEUROSURGERY DEPARTMENT
GAINESVILLE FL 326100265
Business Street:
ROOM L2-100
Department of Neurosurgery
1149 Newell Dr
GAINESVILLE FL 326100001