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UF Health University of Florida
Department of Neuroscience College of Medicine
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Donald C Bolser

Donald C Bolser,

Professor

Department: Department of Physiological Sciences
Business Phone: (352) 294-4026
Business Email: bolser@ufl.edu

On This Page

Accomplishments

Teaching Profile

Courses Taught

  1. VEM5111 – Animal Systems 2

    College of Veterinary Medicine

  2. VEM5112 – Animal Systems 3

    College of Veterinary Medicine

  3. VEM5041 – Animal Welfare/Ethics

    College of Veterinary Medicine

  4. VME7980 – Research for Doctoral Dissertation

    College of Veterinary Medicine

  5. VME5244 – Physiology: Organ Systems

    College of Veterinary Medicine

  6. VEM5110 – Animal Systems 1

    College of Veterinary Medicine

  7. VME6905 – Problems in Veterinary Medical Sciences

    College of Veterinary Medicine

  8. VME6932 – Seminar in Physiological Sciences

    College of Veterinary Medicine

Research Profile

Cough is the most common reason why sick patients visit physicians in the US. This defensive reflex is the most common manifestation of tobacco- and non-tobacco-related pulmonary diseases. Furthermore, cough suppressant (also called antitussive) drugs are among the most commonly prescribed in the world. Significant gaps exist in our understanding of how cough is produced and how this defensive reflex is inhibited by antitussive drugs. The long-range goal of research in our laboratory is to delineate the how the nervous system produces and regulates cough. We use antitussive drugs as tools to determine how the cough system is controlled. As such, our work also will expand our knowledge of the mechanisms by which these drugs inhibit cough. Our current approach incorporates the use of multiple extracellular electrode array technology to investigate the behavior of spontaneously active and recruited neurons in the brainstem during cough. Determination of the identity and functional relationships between these neurons will allow modeling of the configuration of the brainstem cough network. Perturbation of the behavior of these neurons with antitussive drugs will allow us to identify the mechanism by which cough suppressants act to inhibit this behavior.

Publications

Academic Articles

Grants

  1. AB SCIEX QTRAP 7500 LC MS/MS

    Active

    Role:
    Other
    Funding:
    NATL INST OF HLTH OD

  2. Bridge2AI: Voice as a Biomarker of Health – Building an ethically sourced, bioaccoustic database to understand disease like never before

    Role:
    Principal Investigator
    Funding:
    UNIV OF SOUTH FLORIDA via NATL INST OF HLTH OD

  3. Central and Peripheral Regulation of Laryngeal Adduction

    Active

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NHLBI

  4. Influence of Opioids on the Brainstem Respiratory Network

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NHLBI

  5. Modeling the role of the NTS in the neurogenesis of airway defensive behaviors

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH NHLBI

  6. Functional mapping of peripheral and central circuits for airway protection and breathing

    Role:
    Principal Investigator
    Funding:
    NATL INST OF HLTH OD

  7. Modeling the role of the NTS in the neurogenesis

    Role:
    Principal Investigator
    Funding:
    UF FOUNDATION

  8. Brainstem respiratory neuron interactions

    Role:
    Principal Investigator
    Funding:
    UNIV OF SOUTH FLORIDA via NATL INST OF HLTH

Education

  1. PhD – Physiology

    University of South Florida

Contact Details

Phones:
Business:
(352) 294-4026
Emails:
Business:
bolser@ufl.edu
Addresses:
Business Mailing:
PO Box 100144
 GAINESVILLE FL 32610
Business Street:
B3-28
 GAINESVILLE FL 32611