“Membrane potential shapes regulation of dopamine transporter trafficking at the plasma membrane.” Ben D. Richardson, Kaustuv Saha, Danielle Krout, Elizabeth Cabrera, Bruce Felts, L. Keith Henry, Jarod Swant, Mu-Fa Zou, Amy Hauck Newman & Habibeh Khoshbouei. Nature Communications 7, 10423 Abstract:…
Evolution: A sisterly dispute. Telford MJ, Moroz LL, Halanych KM. Nature 2016; 529(7586):286-287. Which phylum first branched off from the animal phylogenetic tree is a contested issue. A new analysis challenges the proposal that comb jellies are the sister group to all other animals, and emphasizes a ‘sponges-first’…
UF Neuroscientists have discovered the mechanics of how dopamine transports into and out of brain cells.
Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis. Hoang-Minh LB, Deleyrolle LP, Siebzehnrubl D, Ugartemendia G, Futch H, Griffith B, Breunig JJ, De Leon G, Mitchell DA, Semple-Rowland S, Reynolds BA, Sarkisian MR. Oncotarget 2016. Abstract: KIF3A, a…
NMDA Receptor Function During Senescence: Implication on Cognitive Performance. Kumar A. Front Neurosci 2015; 9:473. Abstract: N-methyl-D-aspartate (NMDA) receptors, a family of L-glutamate receptors, play an important role in learning and memory, and are critical for spatial memory. These receptors are tetrameric ion channels composed of a…
Non-prion-type transmission in A53T alpha-synuclein transgenic mice: a normal component of spinal homogenates from naive non-transgenic mice induces robust alpha-synuclein pathology. Sacino AN, Ayers JI, Brooks MM, Chakrabarty P, Hudson VJ, III, Howard JK, Golde TE, Giasson BI, Borchelt DR. Acta Neuropathol 2016; 131(1):151-154.
Independent origins of neurons and synapses: insights from ctenophores. Moroz LL, Kohn AB. Philos Trans R Soc Lond B Biol Sci 2016; 371(1685). Abstract: There is more than one way to develop neuronal complexity, and animals frequently use different molecular toolkits to achieve similar functional outcomes. Genomics…
Development of neuromuscular organization in the ctenophore Pleurobrachia bachei. Norekian TP, Moroz LL. J Comp Neurol 2016; 524(1):136-151. Abstract: The phylogenetic position of the phylum Ctenophora and the nature of ctenphore nervous systems are highly debated topics in modern evolutionary biology. However, very little is known about…
