Proteolysis of α-Synuclein Fibrils in the Lysosomal Pathway Limits Induction of Inclusion Pathology. – PubMed – NCBI. Sacino AN, Brooks MM, Chakrabarty P, Saha K, Khoshbouei H, Golde TE, Giasson BI. J Neurochem 2016. // // // Abstract: Progression of α-synuclein inclusion pathology may occur through…
Inhomogeneous distribution of Iba-1 characterizes microglial pathology in Alzheimer’s diseaseJasmin Tischer, Martin Krueger, Wolf Mueller, Ori Staszewski, Marco Prinz, Wolfgang J. Streit and Ingo Bechmann. Version of Record online: 12 JUL 2016 | DOI: 10.1002/glia.23024 Abstract: Microglial dystrophy has recently been described as a morphological phenotype of…
Golde TE. Alzheimer disease: Host immune defence, amyloid-[beta] peptide and Alzheimer disease : Nature Reviews Neurology : Nature Publishing Group A recent study demonstrates that amyloid-β (Aβ) can function as an antimicrobial peptide, and additional data show that bacteria and yeast can seed Aβ deposition…
Traditional neuroscience has focused on correlations between oscillations of the brain’s neurons — rhythmic fluctuations in activity patterns — and behavior.
