We would like to recognize and congratulate the winners of the Poster Session at the Neuroscience Educational & Research Retreat, which was held on Wednesday, August 3, 2016 at the Austin Cary Forest Learning Center. Amrutha Pattamatta First Place – Senior Trainee Lara Ianov & Raphael Perim Second Place –…
Novel antibodies to phosphorylated alpha-synuclein serine 129 and NFL serine 473 demonstrate the close molecular homology of these epitopes. Rutherford NJ, Brooks M, Giasson BI. Acta Neuropathol Commun 2016; 4(1):80. // // // Abstract: Pathological inclusions containing aggregated, highly phosphorylated (at serine129) α-synuclein (αS…
Congratulations to graduate students Jenna Leclerc and Justin Rossi, who all successfully defended their dissertations and graduated in during the Summer 2016 term. Jenna Leclerc (Mentor: Dr. Sylvain Dore): Role of the Haptoglobin-CD163 Scavenging Pathway following Hemorrhagic Stroke Justin Rossi (Mentor: Dr. Michael Okun): Neural Correlates of Impulse Control…
Age-related changes in tonic activation of presynaptic versus extrasynaptic gamma-amniobutyric acid type B receptors in rat medial prefrontal cortex. Carpenter, H.E., Kelly, K.B., Bizon, J.L., Frazier, C.J., 2016. Neurobiol Aging 45, 88-97. Abstract: The present study examined the effect of age on both glutamatergic and γ-aminobutyric acid mediated…
Proteolysis of α-Synuclein Fibrils in the Lysosomal Pathway Limits Induction of Inclusion Pathology. – PubMed – NCBI. Sacino AN, Brooks MM, Chakrabarty P, Saha K, Khoshbouei H, Golde TE, Giasson BI. J Neurochem 2016. // // // Abstract: Progression of α-synuclein inclusion pathology may occur through…
Inhomogeneous distribution of Iba-1 characterizes microglial pathology in Alzheimer’s diseaseJasmin Tischer, Martin Krueger, Wolf Mueller, Ori Staszewski, Marco Prinz, Wolfgang J. Streit and Ingo Bechmann. Version of Record online: 12 JUL 2016 | DOI: 10.1002/glia.23024 Abstract: Microglial dystrophy has recently been described as a morphological phenotype of…
Golde TE. Alzheimer disease: Host immune defence, amyloid-[beta] peptide and Alzheimer disease : Nature Reviews Neurology : Nature Publishing Group A recent study demonstrates that amyloid-β (Aβ) can function as an antimicrobial peptide, and additional data show that bacteria and yeast can seed Aβ deposition…
