Dr. Giasson’s article “Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies” was selected as the representative ‘Neurobiology’ article for the 2018 retrospective collection entitled “The year in JBC: 2018.” Associate editors looked through hundreds of papers to come up with what they felt best represented the exciting advances reported in JBC last year. The issue can be found at https://pubmed.ncbi.nlm.nih.gov/29259137/.