Unbiased View of Synaptic and Neuronal Gene Complement in Ctenophores: Are There Pan-neuronal and Pan-synaptic Genes across Metazoa? Moroz LL, Kohn AB. Integr Comp Biol 2015; 55(6):1028-1049. Abstract: Hypotheses of origins and evolution of neurons and synapses are controversial, mostly due to limited comparative data. Here, we…
Hyperpolarization-activated, cyclic nucleotide-gated cation channels in Aplysia: Contribution to classical conditioning. Yang Q, Kuzyk P, Antonov I, Bostwick CJ, Kohn AB, Moroz LL, Hawkins RD. Proc Natl Acad Sci U S A 2015. Abstract: Hyperpolarization-activated, cyclic nucleotide-gated cation (HCN) channels are critical regulators of neuronal excitability, but…
Forelimb Muscle Plasticity Following Unilateral Cervical Spinal Cord Injury. Gonzalez-Rothi EJ, Armstrong GT, Cerreta AJ, Fitzpatrick GM, Reier PJ, Lane MA, Judge AR, Fuller DD. Muscle Nerve 2015. ABSTRACT: INTRODUCTION: Motor dysfunction and muscle atrophy are well-documented in the lower extremity following spinal cord injury. However the…
Prion-like propagation of mutant SOD1 misfolding and motor neuron disease spread along neuroanatomical pathways. Ayers JI, Fromholt SE, O’Neal VM, Diamond JH, Borchelt DR. Acta Neuropathol 2015. Abstract: A hallmark feature of amyotrophic lateral sclerosis (ALS) is that symptoms appear to spread along neuroanatomical pathways to engulf…
Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke. Frankowski JC, DeMars KM, Ahmad AS, Hawkins KE, Yang C, Leclerc JL, Dore S, Candelario-Jalil E. Sci Rep 2015; 5:17956. Jan Frankowski was HHMI undergraduate working in the laboratory of Dr. Eduardo Candelario-Jalil.
Re-Opening the Critical Window for Estrogen Therapy. Linda A. Bean, Ashok Kumar, Asha Rani, Mike Guidi, Awilda M. Rosario, Pedro E. Cruz, Todd E. Golde, and Thomas C. Foster. The Journal of Neuroscience, December 9, 2015 • 35(49):16077–16093 • 16077 Abstract: A decline in…
Successful aging: Advancing the science of physical independence in older adults. Anton SD, Woods AJ, Ashizawa T, …, Foster TC, et al. Ageing Res Rev 2015; 24(Pt B):304-327. Abstract: The concept of ‘successful aging’ has long intrigued the scientific community. Despite this long-standing interest, a consensus definition…
Contribution of N-methyl-D-aspartate receptors to attention and episodic spatial memory during senescence. Guidi M, Rani A, Karic S, Severance B, Kumar A, Foster TC. Neurobiol Learn Mem 2015; 125:36-46. Abstract: A decrease in N-methyl-D-aspartate receptor (NMDAR) function is associated with age-related cognitive impairments. However, NMDAR antagonists are…
Dr. Louis Ritz, Associate Professor in the Department of Neuroscience, has been identified as a faculty honoree by one of this year's Anderson Scholar Award recipients.
Independent origins of neurons and synapses: insights from ctenophores. Moroz LL, Kohn AB. Philos Trans R Soc Lond B Biol Sci 2016; 371(1685). Abstract: There is more than one way to develop neuronal complexity, and animals frequently use different molecular toolkits to achieve similar functional outcomes. Genomics…
