Eduardo Candelario-Jalil, Ph.D.

Assistant Professor

Department of Neuroscience
University of Florida
1149 Newell Drive
PO Box 100244
Gainesville, FL 32611-0244

Email: ecandelario@ufl.edu
Office Phone: (352) 273-7116
Lab Phone:    (352) 273-6764
Lab Members:   Candelario-Jalil Lab

Education:

2002 Ph.D.
(Neuropharmacology)
University of Havana
Havana, Cuba
2003-2006 Postdoctoral Fellowship
(Molecular Neurobiology)
University of Freiburg Medical School
Germany
2006-2008 Postdoctoral Fellowship
(Neurology/Neuroscience)
University of Mexico
Albuquerque, NM

Key Words:    Ischemic Stroke; Neuroinflammation; Blood-Brain Barrier; Matrix Metalloproteinases; Cerebral Ischemia; Neurovascular Injury

Research Summary: 

Our research is aimed at understanding how neuroinflammatory mechanisms contribute to ischemic stroke pathology with a specific emphasis on the blood-brain barrier (BBB). Neurovascular/BBB damage is a key neuropathological mechanism in stroke, which significantly contributes to brain edema, neurological deterioration, and death in stroke patients. We are interested in cyclooxygenase-2-derived prostaglandins and how signaling through specific prostanoid receptors impact stroke outcomes. We are also studying the neurovascular effects of adropin, a newly identified peptide, on BBB damage after stroke. We expect that results from our research will identify novel and much-needed therapeutic approaches to reduce the devastating consequences of stroke-induced BBB damage.

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